AI-Designed Viruses Successfully Kill Bacteria in Lab Tests

AI-Designed Viruses Successfully Kill Bacteria in Lab Tests

Researchers from the Arc Institute (with collaborators at Stanford) used the Evo family of generative models to design entirely new functional bacteriophage genomes (using ΦX174 as a template). According to the authors, they synthesized and screened about 285 designs; 16 proved functional—replicating and causing lysis of E. coli colonies. The study highlights potential for phage therapy against antibiotic-resistant infections but raises urgent biosafety concerns: such genome-design tools could theoretically be misused to create harmful pathogens, so the authors call for strict oversight. (Source: Arc Institute, bioRxiv preprint, Newsweek coverage).

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